Turning quickly away, the road to the east gives no more relief, as each squat pillar also bears a skeletal mask - two in fact, facing in opposite directions, diagonal one another - which reinforces much of what we are to see in Ikana: the overt and repetitive motif of death, mostly embodied in totems of earthly demise. Limned with crimson forms - which might be alphabetic or simply impressionistic - the entire gateway is marked by an air of worry: that we should look on it frantically, as garish as it is violent, and seek to be rid of it. The Eastern Gate from Clock Town is bound by two dark stones, acting as thick buttresses for the central opening, which is a highly-abstracted skull in pale grey, white, red, and black. These pillars, as well as the gate leading east, all bear what is perhaps the chief motif of Ikana: death masks, either skeletal or merely twisted. Running eastward from Clock Town is a dusty road, given boundaries only by eight stout pillars. Unlike the three other regions of Termina, there are no bustling settlements or amenities for tourists, nor is there the anticipation of festivity and happiness - it is a place that exists in stagnation and ruin, a place whose true time was as long ago as a childhood dream. Eastern Termina is home to mountainous canyons, ancient battlegrounds, and guarded histories it is also home to many creatures only seen within its dusty valleys and ravines, and nowhere else, nor in any other time. And while much could be said on this topic, especially by those of us in Western countries, for it is a large one, let it suffice to say that Majora’s Mask also builds upon this trope of the obscure-yet-enticing East. For much of recorded history, the very mention of the direction brought forth conceptions of mystery, vastness, and deep spirituality. To the Western mind, the East has long been a subject of fascination. Even now it is a place where troubled, regretful spirits gather.” “Ikana Kingdom was founded on this land, stained with a history of darkness, drenched in blood.
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Save time lesson planning by exploring our library of educator reviews to over 550,000 open educational resources (OER).Īn all-in-one learning object repository and curriculum management platform that combines Lesson Planet’s library of educator-reviews to open educational resources with district materials and district-licensed publisher content.Ī comprehensive online edtech PD solution for schools and districts. Timely and inspiring teaching ideas that you can apply in your classroom Manage saved and uploaded resources and foldersīrowse educational resources by subject and topic Search reviewed educational resources by keyword, subject, grade, type, and more The 2018 Monaco Grand Prix (formally known as the Formula 1 Grand Prix de Monaco 2018) was a Formula One motor race that was held on at the Circuit de Monaco, a street circuit that runs through the Principality of Monaco. Since its establishment in 1950, the circuit has. It’s among the last circuits of men, where the skills and talents of drivers play a significant role when it comes to winning. However, there were many other races since the year 1929. The Monaco Grand Prix circuit was the second in history to host an F1 event in 1950, after Silverstone. It first hosted a motor race in 1929 and joined the F1 calendar in 1950. Across the weekend highs of 20 degrees Celsius are predicted – around three degrees cooler than the hottest conditions at the Spanish GP.The Circuit de Monaco is one of the most famous and prestigious tracks in the world. Monaco is set for largely sunny conditions, with some cloud on Saturday and Sunday, with a minimal chance of rain. Photo by: Joe Portlock / Motorsport Images Weather forecast for the Monaco GP All fans are required to follow COVID-19 regulations in the grandstands and around the street track. For the Friday ‘rest day’ the cap is set at 3,000 spectators. Live radio coverage of every practice, qualifying and race for the 2021 F1 season will be available on the BBC Radio 5 Live and 5 Live Sports Extra stations.Ĭoverage of the Monaco GP will start at 1:50pm BST on BBC Radio 5 Live Sports Extra, available on both DAB radio and the BBC Sounds app.ĭue to ongoing COVID-19 restrictions, the Monaco GP spectator attendance allowance is currently capped at 40% of the regular full capacity for the race weekend with a maximum of 7,500 fans permitted on each day of track action. Photo by: Joe Portlock / Motorsport Images Will it be on the radio? Lewis Hamilton, Mercedes AMG F1 W10, leads the field through the first corner Start time: Saturday qualifying 8:00pm, Sunday race 6:30pmĬhannel 4 has the rights to show Monaco GP highlights of qualifying on Saturday and the race on Sunday.Sky Sports has live and exclusive broadcasting rights in the United Kingdom with the build-up to the F1 race starting from 12:30pm ahead of lights out at 2:00pm. Channel numbers – Virgin Media: 506 (Sky Sports F1 HD).Photo by: Joe Portlock / Motorsport Images How can I watch the Monaco GP? While the tradition of the Friday off remains in place, it is now used to allow both traffic to flow through the area plus businesses and hotels to replace stock and prepare for the busy weekend period during the Monaco GP.ĭespite demand on businesses and hotels set to be less due to the COVID-19 restrictions, with attendance capacity capped at 40% or 7,500 fans per each day of track action and only 3,000 fans on Friday, it still allows all fans and visitors to easily move around the region ahead of the main action when the roads are shut again on Saturday and Sunday.īut Friday’s ‘rest day’ still sees track action as Formula 2’s first sprint race will be held that day, starting at 11:45am local time, as part of the F1 support series’ new three-race format. Originally, the Monaco GP fell on a bank holiday weekend in the province, meaning the Friday was kept free to observe the day and allow regular traffic to move through Monte Carlo. Photo by: Joe Portlock / Motorsport Images Why is F1 Monaco GP practice on a Thursday? Lewis Hamilton, Mercedes AMG F1 W10, leads Max Verstappen, Red Bull Racing RB15 Two free practice sessions lasting 60 minutes each (rather than the previous 90-minute sessions) are followed by an additional practice session also running for one hour on Saturday morning. Photo by: Joe Portlock / Motorsport Images 2021 Formula 1 Monaco GP session timingsį1 will continue to run its revised weekend schedule for 2021, with shorter practice sessions on Thursday (for Monaco GP only). While Mercedes appears to have gained the upper-hand against Red Bull, thanks to Hamilton’s three wins from the opening four rounds, the Milton Keynes-based squad will know Monaco represents an ideal opportunity to strike back with the tight and twisty circuit traditionally suiting the characteristics of the team’s car.Īfter a trio of third-place finishes, Valtteri Bottas will also be aiming to join the fight at the front having already fallen off the pace – having scored exactly half the amount of Hamilton’s points tally so far.Īlong with the usual intense midfield fight, four F1 drivers will also make their Monaco GP debut the trio of 2021 rookies in Yuki Tsunoda, Mick Schumacher and Nikita Mazepin plus Williams’ Nicholas Latifi who missed out last year when the race was cancelled. You’ll typically find a game or two as well as accessories like an extra controller or headset. Console deals include the system itself but that’s not all. 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With game consoles, gaming accessories and video games for Xbox, PlayStation and Nintendo consoles, as well as collectibles from your favorite video game franchises, you're sure to find something that you or the gamer in your life will love. Continued abuse of our services will cause your IP address to be blocked indefinitely.As the retailer's name suggests, GameStop is your one stop shop for all of your gaming needs, especially during the GameStop Black Friday sale. Please fill out the CAPTCHA below and then click the button to indicate that you agree to these terms. If you wish to be unblocked, you must agree that you will take immediate steps to rectify this issue. If you do not understand what is causing this behavior, please contact us here. If you promise to stop (by clicking the Agree button below), we'll unblock your connection for now, but we will immediately re-block it if we detect additional bad behavior. 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In the past two decades, our products including Vitamin-R, A Better Finder Rename, A Better Finder Attributes, 'The Big Mean Folder Machine', Photo Date Changer, File Date Changer, Noise Machine and MacBreakZ have firmly established themselves in their respective product categories. in 1996 with the aim of producing affordable best-of-breed software for the Macintosh. Publicspace was founded by Frank Reiff, Ph.D. Vitamin-R for iPhone 1.0.7 is $4.99 USD (or equivalent amount in other currencies) and available worldwide exclusively through the App Store in the Business category. * Vitamin-R is used by many students, especially in Medical School (who will get the joke) to revise for their exam and help them achieve to the best of their abilities. * Vitamin-R was never specifically designed with ADHD “suffers” in mind, but many ADHD-ers have found Vitamin-R’s approach to focusing attention particularly valuable. * Multiple iOS devices and Macs can be kept synchronized easily with Dropbox sync * Vitamin-R provides everything you need to implement the Pomodoro Technique: sophisticated timer, log book and analysis components. You can use it occasionally to overcome procrastination or mental blocks or re-organize your entire working life around the concepts that it embodies. * Vitamin-R plugs into your life rather than trying to take it over. 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This new feature allows users to capture time slices whether they are working on their desks or on the go. Today’s latest release introduces Dropbox sync between the iPhone and the Mac version. The built-in task logging and analysis features create positive momentum towards productivity by providing you with visible feedback on your progress and achievements. Vitamin-R creates optimal conditions for your brain by structuring your work into short bursts of distraction-free, highly-focused activity alternating with opportunities for renewal, reflection and intuition. Canach, Luxembourg – publicspace has brought Vitamin-R, its powerful time boxing solution in the Pomodoro Technique tradition, from the Mac to the iPhone. His imagination and sheer musical brilliance was key in the 60s colouring in records with amazing and imaginative use of strings, working with The Beatles, Marianne Faithful, Billy Fury and a whole host of other key players. In short, he was a pop genius and should be lauded in the way that Joe Meek is. Musically the story had become about Gary Glitter but in reality it should be about the band's producer Mike Leander. People come to the gigs and they understand that the band and the songs are quite separate from the whole situation." But when we do play people really appreciate what we are doing. "It seems like every time we get a series of gigs together and some sort of comeback is on the cards, he will get arrested and we lose a lot of shows. The Glitter Band’s own career has been stymied by the situation. Even then he insisted on staying in a hotel whilst we had to share digs in bunk beds behind the stage. Glitter was difficult to work with even when we first met him in 1964/65 when we were his backing band in the Starr Club in Germany. We were not even that close when we were working with him. The tabloids ring all the time looking for stories but I have nothing to tell. "I've not even spoken to Gary for 30 years and every day I have to speak about him. The band have become entangled in Gary Glitter’s new world and they feel unfairly tarred with the same brush as their former singer, as John Rossal their new leader wearily explains. A fabric that has been torn by Paul Gadd's fall from grace. It's a sound that is part of the fabric of British pop culture. They were also a massive influence on The KLF/Timelords who collaborated with GG, Ed.) ( Even the Cologne techno scene of the early 00s which featured the so-called 'schaffel' rhythm in triplet eights was in thrall to the Glitter beat. It's a sound that is so distinctive that it causes the Pavlovian exhortation: "Ah! The Glitter beat!" They are the last living link to the brilliant producer Mike Leander, who created the Glitter Band sound which has influenced so many people in pop from The Fall to The Smiths to Marilyn Manson, Adam And The Ants, Bow Wow Wow and Killing Joke and anyone else who cops that droning guitar over a tribal beat. The Glitter Band's unique sound is well appreciated by the cognoscenti of alternative music makers. If the Chiefs would not have to pay Glitter, it would squash the biggest criticism from the idea, and perhaps a possible step in bringing back an old Arrowhead tradition-still a favorite of many to this day.They may have played on some of pop’s great records and had a whole career of their own, but now they have to spend every day fending off tabloids and defining themselves against the actions of their former front man. In fact, many Chiefs fans reacted angrily to the article I wrote, saying they don’t want Glitter to receive any royalties.īut given that Glitter does not receive any royalties for his song appearing in Joker, would this change your mind on whether the Chiefs should bring it back? More pertinently, would the Chiefs be willing to bring the tradition back if they did not have to pay Glitter any royalties? Many defended the Chiefs for leaving one of its epic traditions because the team does not want to pay Glitter any royalties. While Glitter was being investigated, the Chiefs used a cover of “Rock ‘N’ Roll Part 2” before parting ways with the song. “We’ve had no contact with him.”Īccording to NME, Universal Music Publishing Group in the United States also confirmed that Glitter would not receive any royalties from them for the use of the song in Joker. “Gary Glitter does not get paid,” the spokesman said to the L.A. Times, a spokesperson from Snapper Music, the London-based label that owns Glitter’s recordings, said that Glitter sold his rights to the recording and publishing of “Rock ‘N’ Roll Part Two”, as well as some of his other songs, more than 20 years ago. If you have seen the new film Joker (no spoilers, I promise), the song is played at one point during the movie. This pencil neck geek is usual on the recieving end of a 36inch long strap on with a girth of 7 inches and only way he can be the giver is riffle a child. Disnt he get caught with a passed out under age male prostitute that he provided drugs to hope he’d be able to sodomize him before he woke up. Time to start getting some American justice from these out of control swamp creatures like Adam shithead schiff. We need to seize his assets to recoup our losses because he thinks he can do what he wants He wasted billions in our taxes over his lies. Adam schiff has that bitch looking face youd enjoy punching. Adam Schiff: “I suspect that all Lindsey Graham wants to do is continue his counter-factual counter-narrative, that is that Donald Trump is somehow the victim when Donald Trump was the one inviting Russians to help him get elected in the first place.” /Vk8PIo9Ghd “I suspect that all Lindsey Graham wants to do is continue his counter-factual counter-narrative, that is that Donald Trump is somehow the victim when Donald Trump was the one inviting Russians to help him get elected in the first place,” Schiff said. That request will be granted.” he added.Īdam Schitt Schiff seemed nervous about the idea of Mueller testifying again now that the DOJ has declassified countless documents proving the special counsel’s Russian collusion investigation was a complete scam. Mueller appear before the Senate Judiciary Committee to testify about his investigation. “Democrats on the Senate Judiciary Committee have previously requested Mr. Mueller is willing – and also capable – of defending the Mueller investigation through an oped in the Washington Post.” – Lindsey Graham said. If you are a Bernie supporter, an HRC supporter - or plan to support another (D) who enters the race, SUPPORT your candidate by pointing out their positions on the important issues, by volunteering for their campaigns, by donating whatever funds you can afford.īuying into the propaganda being spewed by so-called "journalists" serves only one purpose - to lend relevance to people who have none.It has been over a year now since the outbreak of the deadly Corona Virus, loud mouth Adam Schiff has managed to keep his mouth shut and not draw media attention to himself, but it seems all that just came to an end after he went into panic mode over Senator Lindsey Graham’s subpoena threat to Robert Mueller.Īdam Schiff was not too happy about the move by Lindsey Graham to call in Robert Mueller to testify about the sham investigation into Trump-Russia Hoax.Īccording to an article on Gateway Pundit, Senate Judiciary Chairman Lindsey Graham (R-SC) on Sunday announced he will be calling Robert Mueller to testify after the former special counsel blasted Roger Stone in a Washington Post op-ed. The only people who are afraid of anyone on the (D) side are the Clown Car Clan - and everyone knows it, and everyone knows why. Bernie Sanders of Vermont." Reminds me of all the over-the-top bullshit headlines that pop up on FaceBook et al: "Learn why plastic surgeons HATE this Iowa housewife!" "Find out why grocery store chains are TERRIFIED of this Wisconsin farmer!" "Read about how the frozen food industry is PETRIFIED by this Maine fisherman!" " That kind of "reportage" is right up there with "some people are saying".Īnd then there's the caption under Bernie's photo: "Striking fear in the Clinton camp’s heart: Sen. "Insiders familiar with the Clinton campaign’s thinking. Therefore, their only recourse is to gin-up nothing and pretend it's something. This kind of crapola is written and promoted by people who have absolutely nothing of consequence to say. And also energize and rally the forgotten liberal population tired of the excesses of Wall Street and war.Īnd no (D) candidate who winds up running will be afraid of either one of them, or of any other (D) candidate. Its a game, if she can win more of those conservative small r republicans than she loses with "hard core progressives", I'm sure she will welcome him to the race.īernie can counter this by attracting more new younger voters, much like Obama did for his first term win. So she'll most likely win over more center/right independent voters. Bernie will make her look like an old establishment Republican comparatively in the debates. On the other hand, I'm sure her handlers see the silver lining. Maybe instead of cowering in the corner, staying mute and hoping for some faux pas from Bernie that the corporate press can overblow (like Dean's scream) or even start your own rumour mill against him, maybe rethink your positions and who your pals are before all of that. Not being a reactionary war hawk and taking millions in contributions from the MIC? Supporting 99% of the population over 1%?īeing skeptical on secret trade deals written by the corporate class? ".and make her look like a centrist or corporatist" Recently, we have proposed a membrane-based macroencapsulation device consisting of a microwell membrane for islet separation covered by a micropatterned membrane lid. To achieve long-term survival of islets, the device should allow rapid exchange of essential nutrients and be vascularized to guarantee continued support of islet function. Islet encapsulation in membrane-based devices could allow for transplantation of donor islet tissue in the absence of immunosuppression. The best pharmacological, anti-inflammatory, and cellular respiration, metabolism, and energy production effects were observed at high CDCA and nano gel concentrations, suggesting dose-dependent cellular protective and positive effects of CDCA when incorporated with high loading nano gel. Using our established cellular encapsulation system, the Ionic Gelation Vibrational Jet Flow technology, a wide range of CDCA β-cell capsules were produced and examined for morphological, biological, and inflammatory profiles.Ĭapsules' morphology and topographic characteristics remained similar, regardless of CDCA or nano gel concentrations. Accordingly, this study aimed to examine biological effects of various concentrations of CDCA using various solubilising nano gel systems on encapsulated β-cells. One promising approach is the development of nano gels. However, to explore their full potential, formulating such bile acids (that are intrinsically lipophilic) can be challenging, particularly if larger doses are required for optimal pharmacological effects. Recent studies in our laboratory have shown that some bile acids, such as chenodeoxycholic acid (CDCA), can exert cellular protective effects when encapsulated with viable β-cells via anti-inflammatory and anti-oxidative stress mechanisms. Our observations indicate that we should focus on finding or creating a transplantation site that, more than the unmodified peritoneal cavity, permits for close contact between the blood and the encapsulated islet tissue. Our study demonstrates that not only capsular overgrowth but also an imbalance between beta-cell birth and beta-cell death contributes to the failure of encapsulated islet grafts. The necrosis mainly occurred in the center of the islets, which indicates insufficient nutrition as a major causative factor. Necrosis and not apoptosis proved to be the major cause of cell death in the islets. At 4 and 8 weeks postimplant, beta-cell replication was 10-fold higher in encapsulated islets than in islets in the normal pancreas, but these high replication rates were insufficient to prevent a progressive increase in the percentage of nonviable tissue in the islets. Thereafter, we observed a decrease in function rather than in numbers of islets, as illustrated by a decline in the ex vivo glucose-induced insulin response. During the first 4 weeks of implantation, 40% of the initial number of islets was lost. Overgrowth of capsules was complete within 4 weeks postimplant, and it was usually restricted to <10% of the capsules. Grafts were retrieved at 4 and 8 weeks after implantation and at 15.3 +/- 2.3 weeks postimplant, 2 weeks after the mean time period at which graft failure occurred. All recipients of islet allografts became normoglycemic. In search of processes other than overgrowth contributing to graft failure, we have studied the islets in non-overgrown capsules at several time points after allotransplantation in the rat. The survival of microencapsulated islet grafts is limited, even if capsular overgrowth is restricted to a small percentage of the capsules. |
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